Not too long ago, I was dragging through the day. No matter how well I ate or how many hours I slept, I couldn't bounce back. On top of that, my mood was off, and I was catching colds that seemed to linger. One simple blood test later, and the answer was staring me in the face: vitamin D deficiency.
I had no idea how common this was until I dug deeper. And honestly? I wish I had known sooner. Vitamin D is more than just another supplement – it's a critical player in your immune system, mood, bone health, and even your long-term disease risk.
Here's what I learned through my personal health journey and what might help you regain your vitality, too.
✅ Quick Takeaway
Vitamin D supports bones, immunity and mood.
Many people are deficient due to low sun exposure or poor diet.
Fatty fish, egg yolks, and fortified foods are dietary sources.
D3 is preferred over D2 for supplementation and absorption.
Check your levels and supplement wisely – your body will thank you.
What Is Vitamin D?
Let's get one thing straight – vitamin D isn't just a vitamin. Once inside your body, it behaves more like a hormone [1]. It influences over 200 genes and touches just about every major system in your body [2].
Vitamin D is fat-soluble, which means it's stored in your body's fatty tissue. Your body can synthesize vitamin D through exposure to sunlight—specifically UVB rays. But if you spend most of your time indoors or live in a less sunny region, this process becomes less efficient.
According to the National Institutes of Health, vitamin D metabolism is a complex process that begins in the skin and continues in the liver and kidneys, where it's converted to its active vitamin form, calcitriol, which then regulates numerous biological functions throughout the body [3].
There are two main forms:
Vitamin D2 (ergocalciferol): Found in some plants and dietary supplements [4]
Vitamin D3 (cholecalciferol): Found in animal foods and produced naturally in the skin when exposed to sunlight. It's the preferred form for supplementation because it's better absorbed [5].
7 Benefits of Vitamin D
When you think about vitamins that quietly support your body behind the scenes, vitamin D deserves a front-row seat. It doesn't just help you avoid deficiency—it plays a critical role in keeping many systems running smoothly, acting like the conductor of a well-tuned orchestra.
🦴 1. Stronger Bones and Teeth
Vitamin D helps the body absorb calcium and phosphorus, two minerals essential for building and maintaining bone mass [6]. Without enough vitamin D, calcium absorption becomes compromised, increasing the risk of fractures, osteoporosis, and bone-softening diseases like vitamin D deficiency rickets [7].
🛡️ 2. Supports Immune Health
Vitamin D plays a critical role in regulating immune responses [8]. It helps your immune system distinguish between foreign invaders and your own cells, reducing the risk of autoimmune diseases like multiple sclerosis and type 1 diabetes [9]. Low vitamin D levels have also been linked to a higher susceptibility to respiratory infections and slower healing [10].
💓 3. Heart and Cardiovascular Health
Emerging studies suggest that adequate vitamin D levels may help lower the risk of high blood pressure, heart attack, and stroke [11]. A review and meta-analysis found that low vitamin D levels were associated with increased cardiovascular disease risk, although more research is still needed to confirm cause-and-effect relationships [12].
🧠 4. Mental Health and Mood Regulation
Have you ever felt the winter blues? That's no coincidence. Vitamin D influences the production of serotonin, the "feel good" brain chemical that helps regulate mood [13]. Research shows a connection between vitamin D insufficiency and conditions like seasonal affective disorder, depression, and anxiety [14].
🧬 5. May Reduce the Risk of Certain Cancers
Studies show that higher serum 25 hydroxyvitamin D levels are associated with a lower risk of total cancer incidence and cancer mortality [15]. Notable findings include:
Colorectal cancer risk declines with sufficient vitamin D levels [16]
Breast cancer risk is lower in women with higher vitamin D status, particularly postmenopausal women [17]
Prostate cancer risk has also shown associations with vitamin D, though more data is needed [18]
A systematic review and meta of trials suggests daily vitamin D supplementation may reduce breast cancer incidence [19]
🔄 6. Regulates Inflammation
Vitamin D acts as a modulator of inflammation, helping the body fight chronic low-grade inflammation—key in conditions like arthritis, diabetes, and even inflammatory bowel disease [20].
🧓 7. Supports Healthy Aging
Vitamin D supports muscle strength, balance, and bone density – important for reducing falls and fractures in the elderly [21]. It's especially crucial for those with inadequate vitamin D status, chronic kidney disease, or who've had gastric bypass surgery, both of which affect nutrient metabolism [22].
Signs You Might Have Low Vitamin D
Symptoms are often subtle but persistent. Common signs include:
Constant fatigue
Mood swings or mild depression
Frequent infections
Bone or back pain
Muscle weakness
Hair loss
In severe cases, vitamin D deficiency can impair growth, immunity, and energy levels [23].
Risk Factors for Deficiency
You're more likely to have lower vitamin D levels if you:
Spend most of your time indoors [24]
Have darker skin (which reduces UV absorption) [25]
Are elderly or overweight [26]
Have absorption issues (like inflammatory bowel disease) [27]
Have had gastric bypass surgery [28]
Use sunscreen often or wear full-body clothing [29]
Live in areas with limited sunlight [30]
How Much Vitamin D Do You Really Need?
The Dietary Reference Intakes (DRIs) suggest [31]:
Vitamin D levels are measured in ng/mL or nmol/L [32]:
D3 vs D2: What's the Difference?
When you're supplementing, you'll come across vitamin D2 and vitamin D3. While they sound similar, they're not equally effective.
D3 (Cholecalciferol)
Found in: Oily fish, egg yolks, lanolin-based supplements
Your body makes it naturally when exposed to sunlight
More stable and effective at raising serum vitamin D levels
D2 (Ergocalciferol)
Plant-based, used in some fortified foods and vegan supplements
Less bioavailable and breaks down faster in the body
Clinical trials and a review and meta-analysis show that D3 is more effective at raising and maintaining optimal levels [33].
Where to Get Vitamin D Naturally?
1. Sunlight
Your skin can synthesize vitamin D when exposed to UVB rays [34]. 10 to 30 minutes of sun exposure on bare skin (arms, legs, face) a few times a week is usually enough. However, time of day, season, skin tone, and geography all affect how much vitamin D your body actually synthesizes.
2. Vitamin D Rich Foods
There are only a few foods that naturally contain vitamin D [35]. Here are the top sources:
Fatty fish like salmon, sardines, and mackerel are the richest sources. If you're vegan or vegetarian, UV-exposed mushrooms and fortified plant milks are good options.
Supplements: When Food and Sun Aren't Enough
Sometimes, dietary vitamin D intake just isn't enough—especially if you're indoors most of the time or in a higher-risk group. That's where supplements come in.
Most supplements contain D3 (cholecalciferol,) which is more effective than D2. You can find it as:
Capsules or soft gels
Sprays or drops (great for kids)
Part of daily multivitamins
Some people need higher doses to correct a deficiency. In such cases, randomized controlled trials have shown that 1,000–4,000 IU daily are often safe and effective, especially in those with vitamin D insufficiency or chronic kidney disease [41].
Consult your doctor before starting any regimen, especially if you have pre-existing conditions.
How to Optimize Absorption?
Taking vitamin D with food—especially meals with healthy fats—helps absorption [42]. Magnesium and vitamin K2 also work synergistically with vitamin D to ensure calcium metabolism and heart and bone health [43].
Too Much of a Good Thing?
It's possible to have too much vitamin D, especially with high-dose supplements over time. Vitamin D toxicity can cause:
Nausea, vomiting
Excess calcium in the blood
Kidney stones
Weakness and confusion
Stick to the recommended daily intake and check with your doctor if you are supplementing long-term.
Vitamin D and Skin Cancer: A Fine Line
Sunlight helps your body produce vitamin D, but too much can increase your risk of skin cancer [44]. Short, safe periods in the sun without burning are usually enough to synthesize vitamin D naturally without risk.
What Science Says
The science on vitamin D and health is still out. Findings from nutrition examination survey data, review and meta-analysis, and systematic review and meta-studies show links between dietary vitamin D intake, vitamin D levels, and reduction in [45]:
Cancer incidence
Cardiovascular disease
Autoimmune flares
Bone fractures
Breast and colorectal cancer risk
Final Thoughts
I didn't correct my vitamin D deficiency overnight—but once I got my levels up, the changes were undeniable. I had more energy, fewer infections, and more emotional stability. It felt like a cloud had lifted.
If you're tired, in a low mood, or feel "off," don't overlook this little nutrient. One minor tweak—more sun, a better diet, and vitamin D supplements—could mean big improvements in your health and well-being.
The information provided on this website is for general informational and educational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult your physician or other qualified healthcare professional with any questions you may have regarding a medical condition or before starting any health or wellness program.
Bouillon R, Marcocci C, Carmeliet G, et al. Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions. Endocrine Reviews. 2019;40(4):1109-1151. https://academic.oup.com/edrv/article/40/4/1109/5413787 (Accessed on 12 Apr 2025)
Tripkovic L, Lambert H, Hart K, et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. The American Journal of Clinical Nutrition. 2012;95(6):1357-1364. https://academic.oup.com/ajcn/article/95/6/1357/4578292 (Accessed on 12 Apr 2025)
Houghton LA, Vieth R. The case against ergocalciferol (vitamin D2) as a vitamin supplement. The American Journal of Clinical Nutrition. 2006;84(4):694-697. https://academic.oup.com/ajcn/article/84/4/694/4633079 (Accessed on 12 Apr 2025)
Griz LH, Bandeira F, Gabbay MA, Dib SA, Carvalho EF. Vitamin D and diabetes mellitus: an update 2013. Archives of Endocrinology and Metabolism. 2014;58(1):1-8. https://www.scielo.br/j/aem/a/JjKvDDnkDKVncswZ7J9ygCn/ (Accessed on 12 Apr 2025)
Aranow C. Vitamin D and the immune system. Journal of Investigative Medicine. 2011;59(6):881-886. https://jim.bmj.com/content/59/6/881 (Accessed on 12 Apr 2025)
Arnson Y, Amital H, Shoenfeld Y. Vitamin D and autoimmunity: new aetiological and therapeutic considerations. Annals of the Rheumatic Diseases. 2007;66(9):1137-1142. https://ard.bmj.com/content/66/9/1137 (Accessed on 12 Apr 2025)
Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. https://www.bmj.com/content/356/bmj.i6583 (Accessed on 12 Apr 2025)
Wang L, Song Y, Manson JE, et al. Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: a meta-analysis of prospective studies. Circulation: Cardiovascular Quality and Outcomes. 2012;5(6):819-829. https://www.ahajournals.org/doi/full/10.1161/circoutcomes.112.967604 (Accessed on 12 Apr 2025)
Zhang R, Li B, Gao X, et al. Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies. The American Journal of Clinical Nutrition. 2017;105(4):810-819. https://academic.oup.com/ajcn/article/105/4/810/4569695 (Accessed on 12 Apr 2025)
Patrick RP, Ames BN. Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior. The FASEB Journal. 2015;29(6):2207-2222. https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.14-268342 (Accessed on 12 Apr 2025)
Garland CF, Gorham ED. Dose-response of serum 25-hydroxyvitamin D in association with risk of colorectal cancer: A meta-analysis. The Journal of Steroid Biochemistry and Molecular Biology. 2017;168:1-8. https://www.sciencedirect.com/science/article/abs/pii/S0960076016302576 (Accessed on 12 Apr 2025)
McCullough ML, Zoltick ES, Weinstein SJ, et al. Circulating Vitamin D and Colorectal Cancer Risk: An International Pooling Project of 17 Cohorts. Journal of the National Cancer Institute. 2019;111(2):158-169. https://academic.oup.com/jnci/article/111/2/158/5039935 (Accessed on 12 Apr 2025)
Kim Y, Je Y. Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysis. British Journal of Cancer. 2014;110(11):2772-2784. https://www.nature.com/articles/bjc2014175 (Accessed on 12 Apr 2025)
Song ZY, Yao Q, Zhuo Z, Ma Z, Chen G. Circulating vitamin D level and mortality in prostate cancer patients: a dose-response meta-analysis. Endocrine Connections. 2018;7(12):R294-R303. https://ec.bioscientifica.com/view/journals/ec/7/12/EC-18-0283.xml (Accessed on 12 Apr 2025)
McDonnell SL, Baggerly C, French CB, et al. Serum 25-Hydroxyvitamin D Concentrations ≥40 ng/ml Are Associated with >65% Lower Cancer Risk: Pooled Analysis of Randomized Trial and Prospective Cohort Study. PLOS ONE. 2016;11(4):e0152441. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152441 (Accessed on 12 Apr 2025)
Bischoff-Ferrari HA, Willett WC, Orav EJ, et al. A Pooled Analysis of Vitamin D Dose Requirements for Fracture Prevention. New England Journal of Medicine. 2012;367(1):40-49. https://www.nejm.org/doi/full/10.1056/nejmoa1109617 (Accessed on 12 Apr 2025)
Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. The American Journal of Clinical Nutrition. 2000;72(3):690-693. https://academic.oup.com/ajcn/article/72/3/690/4729361 (Accessed on 12 Apr 2025)
Sizar O, Khare S, Goyal A, et al. Vitamin D Deficiency. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan. https://www.ncbi.nlm.nih.gov/books/NBK532266/ (Accessed on 12 Apr 2025)
Slater GH, Ren CJ, Siegel N, et al. Serum fat-soluble vitamin deficiency and abnormal calcium metabolism after malabsorptive bariatric surgery. Journal of Gastrointestinal Surgery. 2004;8(1):48-55. https://link.springer.com/article/10.1016/j.gassur.2003.09.020 (Accessed on 12 Apr 2025)
Matsuoka LY, Ide L, Wortsman J, MacLaughlin JA, Holick MF. Sunscreens suppress cutaneous vitamin D3 synthesis. The Journal of Clinical Endocrinology & Metabolism. 1987;64(6):1165-1168. https://academic.oup.com/jcem/article-abstract/64/6/1165/2653071 (Accessed on 12 Apr 2025)
Macdonald HM, Mavroeidi A, Fraser WD, et al. Sunlight and dietary contributions to the seasonal vitamin D status of cohorts of healthy postmenopausal women living at northerly latitudes: a major cause for concern? Osteoporosis International. 2011;22(9):2461-2472. https://link.springer.com/article/10.1007/s00198-010-1467-z (Accessed on 12 Apr 2025)
Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academy Press, 2010. https://www.ncbi.nlm.nih.gov/books/NBK56070/ (Accessed on 12 Apr 2025)
Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism. 2011;96(7):1911-1930. https://academic.oup.com/jcem/article/96/7/1911/2833671 (Accessed on 12 Apr 2025)
Tripkovic L, Wilson LR, Hart K, et al. Daily supplementation with 15 μg vitamin D2 compared with vitamin D3 to increase wintertime 25-hydroxyvitamin D status in healthy South Asian and white European women: a 12-wk randomized, placebo-controlled food-fortification trial. The American Journal of Clinical Nutrition. 2017;106(2):481-490. https://academic.oup.com/ajcn/article/106/2/481/4557638 (Accessed on 12 Apr 2025)
Webb AR, Kline L, Holick MF. Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. The Journal of Clinical Endocrinology & Metabolism. 1988;67(2):373-378. https://academic.oup.com/jcem/article-abstract/67/2/373/2652586 (Accessed on 12 Apr 2025)
Lu Z, Chen TC, Zhang A, et al. An evaluation of the vitamin D3 content in fish: Is the vitamin D content adequate to satisfy the dietary requirement for vitamin D? The Journal of Steroid Biochemistry and Molecular Biology. 2007;103(3-5):642-644. https://www.sciencedirect.com/science/article/abs/pii/S096007600600347X (Accessed on 12 Apr 2025)
Calvo MS, Whiting SJ, Barton CN. Vitamin D fortification in the United States and Canada: current status and data needs. The American Journal of Clinical Nutrition. 2004;80(6):1710S-1716S. https://academic.oup.com/ajcn/article/80/6/1710S/4690516 (Accessed on 12 Apr 2025)
Mattila P, Ronkainen R, Lehikoinen K, Piironen V. Effect of household cooking on the vitamin D content in fish, eggs, and wild mushrooms. Journal of Food Composition and Analysis. 1999;12(3):153-160. https://www.sciencedirect.com/science/article/abs/pii/S0889157599908266 (Accessed on 12 Apr 2025)
Keegan RJ, Lu Z, Bogusz JM, Williams JE, Holick MF. Photobiology of vitamin D in mushrooms and its bioavailability in humans. Dermato-endocrinology. 2013;5(1):165-176. https://www.tandfonline.com/doi/full/10.4161/derm.23321 (Accessed on 12 Apr 2025)
Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. The American Journal of Clinical Nutrition. 2003;77(1):204-210. https://academic.oup.com/ajcn/article/77/1/204/4689654 (Accessed on 12 Apr 2025)
Dawson-Hughes B, Harris SS, Palermo NJ, et al. Meal conditions affect the absorption of supplemental vitamin D3 but not the plasma 25-hydroxyvitamin D response to supplementation. Journal of Bone and Mineral Research. 2013;28(8):1778-1783. https://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.1896 (Accessed on 12 Apr 2025)